Barretts esophagus be is the precursor to esophageal adenocarcinoma eac a disease with increasing burden in the western world especially in white men risk factors for be include obesity tobacco smoking and gastroesophageal reflux disease gerd eac is the most common form of esophageal cancer in the united states risk factors include gerd tobacco smoking and obesity whereas nonsteroidal antiinflammatory drugs and statins may be protective factors predicting progression from . Barretts esophagus be a metaplastic columnar epithelium of the distal esophagus is the known precursor lesion for ea ea and be occur more frequently in white men over 50 years old as well as in people with frequent symptoms of gastroesophageal reflux in smokers and in people who are obese. Esophageal adenocarcinoma eac is a major cause of cancer related morbidity and mortality in western countries the incidences of eac and its precursor barretts esophagus be have increased. The number of cases of esophageal adenocarcinoma now exceeds those of squamous cell carcinoma in western countries and the annual number of cases of barretts esophagus leading to esophageal
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